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The Time & Life Building, located at 1271 Avenue of the Americas in Midtown Manhattan, is a significant skyscraper completed in 1958 under the architectural guidance of Wallace K. Harrison. As part of the Rockefeller Center complex, it stands near notable structures like the RCA and GE Buildings. Designed for Time Inc., the building features a flexible steel frame and glass-walled upper floors, allowing for adaptable office spaces crucial for a media company with diverse needs.

Originally owned by Time Inc., it was later acquired by the Rockefeller Foundation and other entities before undergoing a modernizing renovation in 2014, retaining original architectural elements like marble floors and brass details. The building's design has been lauded for its aesthetic appeal, particularly its lobby, though some critics find the exterior less striking.

Influential in urban architecture, it inspired similar designs along Sixth Avenue. Its cultural significance extends to appearances in TV shows like Mad Men and movies, enhancing its iconic status. Despite challenges during the COVID-19 pandemic, the building achieved LEED Gold certification, reflecting a commitment to sustainability and remains a vibrant hub for various tenants including financial firms, law offices, and Major League Baseball's store.

In summary, the Time & Life Building is notable for its blend of practical functionality and aesthetic design, successfully adapting over decades while maintaining architectural integrity. Its influence on urban development and cultural impact underscore its importance in Manhattan's skyline.